San Francisco has won four of their last seven games, including last week's big win over the Raiders. But this will be a tough one for the Niners. San Diego is a far more talented ballclub, and the offense will definitely be without TE Vernon Davis and could also find themselves without the entire left side of the offensive line thanks to injuries to T Jonas Jennings (finger) and G Larry Allen (knee). I think San Diego wins this one going away, 28-7.
Don't forget to post your predictions for this game as our
$300 Ticket Contest continues! Just correctly predict the winner and the final score of this game, or any NFL, college football or MLB baseball playoff game, and you could be eligible to win free seats to see your favorite team play live! Check out
the official contest rules thread for more details, and good luck!