[simple simon]

Are the Bills really better at linebacker without Takeo Spikes and London Fletcher?
A follow-up question is whether the Bills are as good at running back with Marshawn Lynch replacing Willis McGahee. Naturally, the Bills wanted Patrick Willis to be their first-round pick. He would have been the anchor to their linebacking corps, but the 49ers drafted him one spot ahead of the Bills. Marv Levy believes he found a new Shane Conlin with the second-round selection of Paul Posluszny.

Spikes and Fletcher are gone, so the linebacking group has been completely overhauled. With a defensive line that isn't dominating, it is hard to tell whether the defense is even better. Making things worse is the loss of Nate Clements at cornerback. The Bills are hoping to get by with Terrence McGee and Ashton Youboty. As a low-revenue team, the Bills have to cut some financial corners. It remains to be seen whether they cut their collective throats by losing too many key defenders.
ESPN.com - NFL - Clayton: AFC big questions

[Lefty Noob]

I like their draft, and Pos will be good. But you don't just up and replace an athlete who brings the kind of impact potential that Spikes has. I'm guessing they just got fed up with all his injuries, but their defense will really struggle this season because they just don't seem to have enough veteran leadership, nor enough impact players, on that side of the ball.

[simple simon]

they will probably be fighting the Dolphins for last place in the East